|
KMID : 0858420070090010056
|
|
Korean Journal of Stroke
2007 Volume.9 No. 1 p.56 ~ p.61
|
|
|
Coincidental Abnormality of Anterior Cerebral Artery in Patients with Acute Middle Cerebral Artery Occlusion
|
|
Park Tae-Hwan
Kim Min-Ky
Chung Chin-Sang
Kim Gyeong-Moon
Ha Sam-Yeol
Lee Kwang-Ho
|
|
|
Abstract
|
|
|
Background: Anterior cerebral artery (ACA) can play a great role as a collateral flow to the hypoperfused middle cerebral artery (MCA) territory. We investigated angiographic findings of the ipsilateral ACA in patients with acute MCA occlusion, and analyzed the clinical impact of vascular abnormalities of the ACA (VAA).
Methods: We retrospectively analyzed the angiographic findings of the ACA in 29 patients recieved who intra-arterial thrombolysis (IAT) within 6 hours after symptomatic MCA occlusion. VAA was defined as occlusion or stenosis over 50% presents in any branches of the ACA. Risk factors, serial National Institutes of Health Stroke Scale (NIHSS) scores, immediate recanalization rates, symptomatic intracranial hemorrhage (SICH), and modified Rankin Scale (mRS) scores were compared between patients with and without VAA.
Results: Eleven (38%) patients showed VAA (5 occlusions, 6 stenosis). Patients with VAA had a significantly higher baseline median NIHSS score than patients without (17 vs. 10.5, P<.01). Immediate recanalization rate (55% vs. 67%), occlusion site of MCA, and risk factors were not different between patients with and without VAA. SICH had a tendency to occur among patients with VAA (45.5% vs. 16.7%, P=.106). Follow up median NIHSS score at 1 day (16 vs. 8, P<.01), and 7 day (13 vs. 4, P<.01) after stroke were higher in patients with VAA. Independency rate (mRS ≤2 at 30 day after stroke) was less common in patients with VAA (18% vs. 61%, P=.029).
Conclusion: Occlusion or stenosis of the ACA branches among patients with acute MCA occlusion is related with severity of stroke and unfavorable outcome after IAT. (Korean Journal of Stroke 2007;9:56-61)
|
|
|
KEYWORD
|
|
|
Middle cerebral artery occlusion, Anterior cerebral artery, Thrombolysis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|